This brochure explains the science linking aluminum adjuvant and autism. Download, print, and distribute.
Printed color brochures are available. Send inquiries here: http://vaccinepapers.org/contact-form/
There are four versions, in color and B&W, and 2 sizes.
Size 8.5 x 11:
Black and White (printer friendly): Autism-brochure-BW-8.5×11
Color: Autism-brochure-Color-8.5×11
Size A4:
Black and White (printer friendly): Autism-brochure-BW-A4
Color: Autism-brochure-Color-A4
References:
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3) Estes et al, 2015, Immune mediators in the brain and peripheral tissues in autism spectrum disorder, Nature Reviews-Neuroscience. Immune mediators in the brain and peripheral tissues in autism spectrum disorder
4) Deverman and Patterson 2009, Cytokines and CNS Development, Cell. Cytokines and CNS Development
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6) Parker-Athill et al, 2010 Maternal immune activation and autism spectrum disorder: Interleukin-6 signaling as a key mechanistic pathway, Neurosignals. Maternal Immune Activation and Autism Spectrum Disorder: Interleukin-6 Signaling as a Key Mechanistic Pathway
7) Wei et al, 2013, Brain IL-6 and autism, Neuroscience. Brain IL-6 and autism
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10) Wei et al 2011, IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation, Journal of Neuroinflammation. IL-6 is Increased in the Cerebellum of Autistic Brain and Alters Neural Cell Adhesion, Migration and Synaptic Formation
11) Wei et al 2012, Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors. Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
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13) Galic et al, 2008, Postnatal inflammation increases seizure susceptibility in adult rats, Journal of Neuroscience. http://www.jneurosci.org/content/28/27/6904.full
14) Li et al 2015, Neonatal vaccination with bacillus Calmette–Guérin and hepatitis B vaccines modulates hippocampal synaptic plasticity in rats, Journal of Neuroimmunology. Neonatal vaccination with bacillus Calmette-Guérin and hepatitis B vaccines modulates hippocampal synaptic plasticity in rats.
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21) Zager et al., Maternal immune activation in late gestation increases neuroinflammation and aggravates experimental autoimmune encephalomyelitis in the offspring, Brain, Behavior, and Immunity. Maternal immune activation in late gestation increases neuroinflammation and aggravates experimental autoimmune encephalomyelitis in the offspring
22) Shi et al, 2009, Activation of the maternal immune system alters cerebellar development in the offspring, brain, Behavior, and Immunity. Activation-of-the-Maternal-Immune-System-Alters-Cerebellar-Development-in-the-Offspring
23) Giulivi et al, 2013, Gestational Exposure to a Viral Mimetic Poly(I:C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring, Mediators of Inflammation. Gestational Exposure to a Viral Mimetic Poly(I-C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring
24) Garay et al, 2012 Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development, Brain, Behavior, and Immunity. Maternal immune activation causes age and region-specific changes in brain cytokines in offspring throughout development.
25) Hsaio et al, 2013, The microbiota modulates gut physiology and behavioral abnormalities associated with autism, Cell. The microbiota modulates gut physiology and behavioral abnormalities associated with autism
26) Bauman et al., 2014, Activation of the Maternal Immune System During Pregnancy Alters Behavioral Development of Rhesus Monkey Offspring, Biological Psychiatry. Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring
27) Shaw and Petrik 2009, Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration, Journal of Inorganic Biochemistry. Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
28) Petrik et al, 2007, Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice, Neuromolecular Medicine. Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice
29) Shaw et al, 2013, Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes, Journal of Inorganic Biochemistry. Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes
30) Crepeaux et al 2017, Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity, Toxicology. Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity
31) Khan et al, 2013, Slow CCL2-dependent translocation of biopersistent particles from muscle to brain, BMC Medicine. Slow CCL2-dependent translocation of biopersistent particles from muscle to brain
32) Alawdi et al, 2016, Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling; Molecular Neurobiology. Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling.
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39) Jie et al., 2015 Core Symptoms of Autism Improved After Vitamin D Supplementation, Pediatrics. Core Symptoms of Autism Improved After Vitamin D Supplementation
40) VP article on healthy user bias: http://vaccinepapers.org/healthy-user-bias-why-most-vaccine-safety-studies-are-wrong/
41) Zerbo et al., 2017 Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder , JAMA Pediatrics. Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder
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